Since the 1960s, research has suggested that zinc is important for wound healing. Further studies have shown that zinc plays a vital role in many of our bodies' cell functions, including those for healing incisional/surgical wounds. At a 1995 meeting of the European Tissue Repair Society (ETRS), zinc's role in the reconstruction and function of collagen in scar tissue was emphasized.*


Parisi AF, Vallee BL. Zinc metalloenzymes: characteristics and significance in biology and medicine. Am J Clin Nutr 1969; 22:1222-29.

Landsdown ABD. Influence of zinc oxide on the closure of open skin wounds: an experimental study. Int J Cosmet Sci 1993; 15:83-85.

Heng MK, Song MK, Heng MCY. Reciprocity between tissue calmodulin and CMAP levels: modulation by excess zinc. Br J Dermatol. 1993; 129:280-85.

Occleston NL, Tarnuzzer RX, Burslem F, et al. Matrix metalloproteinases: an essential component of cell mediated collagen contraction. 5th Annual Meeting European Tissue Repair Society, Padova, Italy, 1995 (abstr 111).

Berger MM, Baines M, Raffoul W, et al. Trace element supplementation after major burns modulates antioxidant status and clinical course by way of increased tissue trace element concentrations. Am J Clin Nutr. 2007;85(5):1293-1300.

*Disclaimer:  If you suffer from any medical illness or have medical concerns or questions, please speak with your healthcare provider. The information on wound healing found on this site is derived from peer-reviewed research and information drawn from medical societies and governmental agencies, links to which are available under “Sources.” However, they are not a substitute for professional medical advice, diagnosis, or treatment.