Thiamine, also known as vitamin B1, has been shown by many studies to improve formation of collagen. Formation of collagen is vital in healing a wound as collagen helps to provide strength to the wound. In surgical incisions, having increased and more rapid collagen formation speeds up the recovery process by making the incision stronger sooner.*


Alvarez OM, Gilbreath RL. Thiamine influence on collagen during the granulation of skin wounds. J of Surg Res 1982; 32:24-31.

Paui HE, Paul MF, Taylor JD, Marsters RW. Biochemistry of wound healing. 1. The thiamine content of healing tissue of skin wounds. Arch Biochem 1945;7:231-237

Sriram K, Manzanares W, Joseph K. Thiamine in Nutrition Therapy. Nutr in Clin Prac 2012;27:41-50.

Utley R. Nutritional factors associated with wound healing in the elderly. Ostomy Wound Manage. 1992;38(3):22-27.

*Disclaimer:  If you suffer from any medical illness or have medical concerns or questions, please speak with your healthcare provider. The information on wound healing found on this site is derived from peer-reviewed research and information drawn from medical societies and governmental agencies, links to which are available under “Sources.” However, they are not a substitute for professional medical advice, diagnosis, or treatment.